MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) : SEND

  • Exam Code: SEND
  • Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
  • Updated: Jul 04, 2026
  • Q & A: 200 Questions and Answers

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MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:

1. A 55-year-old man with type 2 diabetes mellitus presented with foot swelling and discomfort. He had a peripheral sensory neuropathy attributed to diabetes mellitus. A midfoot Charcot's arthropathy was suspected, and a plain X-ray was arranged (see image).

Which is the talonavicular joint?

A) 3
B) 2
C) 4
D) 5
E) 1


2. A 17-year-old boy was concerned about his height. He had been treated for Crohn's disease since the age of 13 with a combination of topical and systemic corticosteroids and azathioprine. He was currently taking mercaptopurinE.
On examination, his height was on the 25th centile.
Investigations:
X-ray of right kneesee image

What is the most appropriate next step in management?

A) refer for leg lengthening surgery
B) investigate for growth hormone deficiency
C) treat with growth hormone
D) advise him that growth is complete
E) advise him that he will continue to grow for 12 months


3. A 73-year-old man had been attending the diabetes clinic for 6 weeks with an ulcer on his right second metatarsal head. He had been receiving regular podiatry and offloading.
What new feature in the appearance of his foot is most likely to suggest the need to start antibiotics?

A) tracking sinus
B) increase in ulcer size
C) skin redness around ulcer
D) ulcer probing to bone
E) pain around ulcer


4. A 56-year-old man was referred to the diabetes clinic for conversion to insulin. He was taking metformin 1 g three times daily, gliclazide 160 mg twice daily and pioglitazone 45 mg daily. He drank no alcohol.
On examination, his body mass index was 41 kg/m2 (18-25). Abdominal examination showed a 2-cm, smooth, non-tender liver edge.
Which liver function test is the best marker of non-alcoholic fatty liver disease in type 2 diabetes mellitus?

A) gamma glutamyl transferase
B) bilirubin
C) alkaline phosphatase
D) aspartate aminotransferase
E) alanine aminotransferase


5. A 19-year-old man was seen in the diabetes clinic. He had lost 2 kg in weight since the diagnosis of diabetes mellitus 18 months previously. At presentation, his body mass index was 33 kg/m2 (18-25), his random plasma glucose was 18.0 mmol/L and his haemoglobin A1c was 56 mmol/mol (20-42). He was taking gliclazide, and metformin had been added later. His father and grandfather had developed diabetes mellitus during their twenties.
Investigations:
haemoglobin A1c56 mmol/mol (20-42)
serum C-peptide301 pmol/L (180-360)
anti-glutamic acid decarboxylase (GAD)
antibodiesnegative
What is the most likely diagnosis?

A) latent-onset diabetes of autoimmunity
B) type 1 diabetes mellitus
C) type 2 diabetes mellitus
D) maturity-onset diabetes of the young
E) chronic pancreatitis


Solutions:

Question # 1
Answer: B
Question # 2
Answer: D
Question # 3
Answer: C
Question # 4
Answer: E
Question # 5
Answer: D

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